Naloxone and Opioid Overdose Prevention

What are Opioids?

Opioids are drugs that are derived from the opium plant or created synthetically to mimic the chemical composition of opium. Opioids are prescribed for pain management or addiction treatment, but they can be abused.

On average, 136 Americans die every day from an opioid overdose (CDC, 2021). In Massachusetts, there were 2,234 confirmed deaths in the year 2021 (MDPH Data Brief, 2022).

Naloxone facts and formulations

Naloxone is a life-saving drug that reverses the effects of opioids like heroin and fentanyl. Giving naloxone to someone who has overdosed prevents death by restoring normal breathing.

Getting Naloxone from a Pharmacy

Naloxone rescue kits are available at many pharmacies across the state, with or without prescriptions.

How to Reverse an Overdose

Learn how to administer naloxone, to stop an overdose and save a life.


MA Current Opioid Statistics

MA Responds to the Opioid Epidemic

MA Stop an Overdose with Naloxone

MA Protect Your Kids from Prescription Drug Use

CDC Understanding the Opioid Overdose Epidemic

Partnership to End Addiction

Al-Anon Family Groups of Massachusetts

Rehab & Treatment Helpline

Alcohol and Drug Hotline: 800-821-4357 

Health Helpline: 800-272-4323

Hunger Hotline: 617-523-7010

MA Substance Abuse Information Hotline: 800-327-5050

National Drug and Alcohol Treatment: 800-662-HELP

Poison Control: 800-682-9211

Safe Link Hotline: 877-785-2020

Samaritans (suicide help line): 988 Call or Text 24/7